|
rs948562
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
|
rs948562
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Lack of association between DNA base excision repair gene XRCC1 Gln399Arg polymorphism and risk of malignant lymphoma in Japan.
|
15104288 |
2004 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this work, we retrospectively evaluated the influence of an XRCC1 polymorphism (rs25487) on the treatment results in a series of 73 patients with lymphoma subjected to ASCT.
|
21463129 |
2011 |
|
rs1800975
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility.
|
23818366 |
2013 |
|
rs1346044
|
|
|
0.010 |
GeneticVariation |
BEFREE |
WRN Cys1367Arg was associated with decreased risk of NHL overall (OR: 0.71; 95% CI: 0.56-0.91; P=0.007) and DLBCL (OR: 0.66; 95% CI: 0.45-0.95; P=0.024), as well as follicular and marginal zone lymphomas.
|
16738949 |
2006 |
|
rs1351687973
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change.
|
11461077 |
2001 |
|
rs535311760
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change.
|
11461077 |
2001 |
|
rs11540652
|
|
|
0.720 |
GeneticVariation |
BEFREE |
This was associated with a twofold higher T-lymphoma proliferation in R248Q/- mice compared with G245S/- and null mice.
|
23538418 |
2013 |
|
rs11540652
|
|
T |
0.720 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs11540652
|
|
|
0.720 |
GeneticVariation |
BEFREE |
We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%.
|
28300840 |
2017 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through searching PubMed databases (or hand searching) up to April 2012 using the following MeSH terms and keywords: "p53", "codon 72" "polymorphism" and "leukemia", or "lymphoma", or "myeloma", thirteen were identified as eligible articles in this meta-analysis for p53 Arg72Pro polymorphism (2,731 cases and 7, 356 controls), including nine studies on leukemia (1,266 cases and 4, 474 controls), three studies on lymphoma (1,359 cases and 2,652 controls), and one study on myeloma.
|
23029260 |
2012 |
|
rs1131691014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through searching PubMed databases (or hand searching) up to April 2012 using the following MeSH terms and keywords: "p53", "codon 72" "polymorphism" and "leukemia", or "lymphoma", or "myeloma", thirteen were identified as eligible articles in this meta-analysis for p53 Arg72Pro polymorphism (2,731 cases and 7, 356 controls), including nine studies on leukemia (1,266 cases and 4, 474 controls), three studies on lymphoma (1,359 cases and 2,652 controls), and one study on myeloma.
|
23029260 |
2012 |
|
rs1555525126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change.
|
11461077 |
2001 |
|
rs28934578
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%.
|
28300840 |
2017 |
|
rs563378859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We propose that similarly to typical human MCL and its blastoid or cyclin-D1 variants that correspond to the same genetic entity, MCL-like lymphomas of c-myc-3'RR/ p53+/- mice and c-myc-3'RR/Cdk4(R24C) mice represent a spectrum of the same entity.
|
22592113 |
2012 |
|
rs867114783
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TP53(R167H/R167H) mutant pigs primarily developed lymphomas and osteogenic tumors, recapitulating the tumor types observed in mice and humans expressing orthologous TP53 mutant alleles.
|
25105366 |
2014 |
|
rs878854066
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through searching PubMed databases (or hand searching) up to April 2012 using the following MeSH terms and keywords: "p53", "codon 72" "polymorphism" and "leukemia", or "lymphoma", or "myeloma", thirteen were identified as eligible articles in this meta-analysis for p53 Arg72Pro polymorphism (2,731 cases and 7, 356 controls), including nine studies on leukemia (1,266 cases and 4, 474 controls), three studies on lymphoma (1,359 cases and 2,652 controls), and one study on myeloma.
|
23029260 |
2012 |
|
rs879253942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The discovery of MYD88 L265P mutations in the vast majority of LPLs has had a major impact on the study of these lymphomas.
|
26454445 |
2016 |
|
rs867830180
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein we performed a case-control study evaluating the influence of three single nucleotide polymorphisms (SNPs) in XPA, ERCC5 and MTR [rs1800975 (G-4A), rs17655 (Asp1104His) and rs1805087 (A2756G), respectively] in lymphoma risk.
|
23818366 |
2013 |
|
rs61756766
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both the SS-lymphoma and SS-nonlymphoma patient subgroups exhibited significantly higher frequencies of the His159Tyr BAFF-R mutation compared to healthy controls (8.6% of SS-lymphoma patients and 6.2% of SS-nonlymphoma patients versus 1.7% of healthy controls; P = 0.02 and P = 0.04, respectively).
|
26097183 |
2015 |
|
rs2230926
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The rs2230926 exonic variant was associated with an increased risk for pSS complicated by lymphoma (odds ratio, 3.36 [95% confidence interval, 1.34-8.42], and odds ratio, 3.26 [95% confidence interval, 1.31-8.12], vs controls and pSS patients without lymphoma, respectively; P = .011).
|
24159176 |
2013 |
|
rs2230926
|
|
|
0.040 |
GeneticVariation |
BEFREE |
However, the rs2230926 variant allele seems to confer a higher risk to develop lymphoma in pSS patients, while in RA patients, the presence of RF resulted significantly associated with the variant allele.
|
31534975 |
2019 |
|
rs2230926
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A germline and coding polymorphism (rs2230926) of TNFAIP3 (A20), a central gatekeeper of nuclear factor-kappa B (NF-kB) activation, was recently found associated with primary Sjögren's syndrome (pSS)-associated lymphoma in a French cohort.We aimed to replicate this association.
|
26338037 |
2016 |
|
rs2230926
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Increased prevalence of the rs2230926 mutant variant was detected in both SS-lymphoma and SS-nonlymphoma subgroups compared to HC (8.8% vs. 7.6% vs. 3.6%, <i>p</i> values: 0.04 and 0.03, respectively) in association with higher IgM, LDH serum levels, and PB <i>Bcl-XL</i> transcripts but lower leucocyte and neutrophil counts.
|
30662920 |
2018 |